Bowden was born in Wyckoff, New Jersey where she got her start in acting and modeling.

Bowden attended the now defunct Saint Thomas More School in Midland Park, NJ, for her grammar and middle school education. She later attended Immaculate Heart Academy in Washington Township, Bergen County, New Jersey.

In 2006 she signed on in a two episode-arc on the ABC daytime soap opera television series One Life to Live as Britney. She guest starred in an episode of Law & Order: SVU.

In 2006 Katrina signed on in the NBC sitcom television series 30 Rock. She portrays the laid back, dopey, sexy assistant, Cerie Xerox. The series premiered October 11, 2006 and stars Tina Fey, Alec Baldwin and Tracy Morgan. She signed on as a series regular for the second season.

In 2008 she starred in Summit Entertainment's Sex Drive in a supporting role as "Ms. Tasty". In 2010 she guest starred in an episode of the ABC series Ugly Betty portraying Heather.